Knowledge · Multidrug-Resistant Organisms

    Multidrug-Resistant Organisms (MRO)

    MRSA, MDRGN, VRE – Significance for surface hygiene.

    Multidrug-resistant organisms pose an increasing challenge. Their resistance to antibiotics complicates therapy and makes prevention all the more important.

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    Multidrug-Resistant Organisms (MRO)

    Classification

    The most important multidrug-resistant organisms

    MRO are classified according to type and extent of their antibiotic resistance.

    MRSA

    Methicillin-resistant Staphylococcus aureus

    Resistance to beta-lactam antibiotics. One of the most common MRO.

    MDRGN

    Multidrug-resistant gram-negative bacteria

    Resistance to multiple antibiotic groups. Classified as 3MDRGN and 4MDRGN.

    VRE

    Vancomycin-resistant Enterococci

    Resistance to vancomycin. Particular significance in intensive care.

    Pathogen Profile

    Why MRO are particularly problematic

    Antibiotic resistance

    MRO are resistant to multiple antibiotics.

    Long survival time

    MRO can survive on surfaces for weeks to months.

    Nosocomial transmission

    Transmission via contact surfaces and hands.

    Institutional spread

    Particular risk in hospitals and care homes.

    Transmission

    Transmission routes of MRO

    Transmission occurs predominantly through direct and indirect contact.

    Colonised/infected patient
    Contaminated hands
    Contaminated surfaces
    Transmission to further patients

    Key contact surfaces

    Bed railsDoor handlesWork surfacesMedical devicesSanitary areasHandrails

    Measures

    Hygiene measures for MRO

    Control requires a bundle of coordinated hygiene measures.

    1

    Hand hygiene

    Consistent hand disinfection.

    2

    Surface disinfection

    Regular wipe disinfection.

    3

    Barrier measures

    Protective gowns, gloves, masks.

    4

    Isolation

    Spatial separation.

    5

    Screening

    Targeted swab tests.

    6

    Documentation

    Complete recording.

    Requirements

    Requirements for surface disinfection

    Disinfectants must be effective against MRO and suitable for routine use.

    Bactericidal efficacy

    Proven efficacy against MRO.

    Short contact times

    Practical contact times.

    Material compatibility

    Gentle on medical surfaces.

    User safety

    Staff protection.

    KRINKO 2022

    KRINKO recommendations for MRO prevention

    KRINKO provides recommendations for handling MRO.

    Risk assessment

    Facilities should perform a risk assessment.

    Basic hygiene

    Consistent implementation of basic hygiene.

    Extended measures

    Additional measures for certain MRO.

    Information transfer

    Structured transfer on discharge.

    System approach

    CleaningBox and MRO prevention

    The CleaningBox system supports systematic surface disinfection.

    DesiMops

    Bactericidal

    Routine surface disinfection – effective against MRO like MRSA and MDRGN.

    C-STOP WIPES

    Sporicidal

    Broad-spectrum disinfection for highest requirements.

    Outbreak management

    Measures for MRO clusters

    Structured countermeasures are required when MRO are detected in clusters.

    1
    MRO detection/cluster
    2
    Isolation & barrier measures
    3
    Intensified surface disinfection
    4
    Screening & monitoring
    5
    Documentation & reporting

    Learn more about MRO prevention

    Modern solutions for safe surface disinfection in the context of multidrug-resistant organisms.

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